Antioxidant properties of various solvent extracts of leaf and tuberous root of Decalepis nervosa [Wight & Arn.] Venter

Divya R., Saradha M., Divya Bharathi G., Vishnu Kumar S.

Abstract


Indian medicinal plants widely have been used for thousands of years in a traditional system of medicine. Decalepis nervosa is one among crucial medicinal plant belonging to the family Apocynaceae. The study aimed to investigate the antioxidant potential of Decalepis nervosa. The different solvents like petroleum ether, Chloroform, ethyl acetate, methanol and aqueous extract of leaf and tuberous root of Decalepis nervosa were analyzed for various methods of free radical scavenging activity such as DPPH*radical scavenging activity, ABTS·+scavenging activity, Reducing power assay, Nitric oxide radical scavenging assay, Superoxide radical scavenging activity. Among the extracts analyzed, the methanol extract of leaf (18.1µg/ml) and tuberous root (21.33 µg/ml) showed better IC50values for DPPH radical scavenging activities compared to other solvent extracts. The methanol extract of leaf showed better ABTS cation radical scavenging activity (74.96µg TE/g extract) than that of tuberous root (70.45µg TE/g extract). The methanol extracts were found to be an efficient scavenger of superoxide radicals in which leaf is found to have the highest activity of 84.27% and tuber 58.89%. In reducing power, methanol showed the highest radical scavenging activity in both leaf and tuber extracts. In all the methods, the methanol extract exhibited good scavenging activity, and this evidenced that the Decalepis nervosa is a potent antioxidant agent.

Keywords


Decalepis nervosa; antioxidant agent; DPPH





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