Toxicity studies of Ervatamia coronaria Stapf., leaves on experimental animals

Gomathi Periasamy

Abstract


The present study was carried out to evaluate the toxicity methanol extract Ervatamia coronaria leaves (MEEC) on experimental animals.  This was determined by the administration of MEEC intraperitoneally to male mice weekly at a single dose of 200 mg/kg for 6 weeks. The results of this study showed no abnormalities in the test groups as compared to the controls. Biochemical and renal parameters values in treated groups were normal in comparison with the control group. Therefore, the methanol extract of MEEC given intraperitoneally to male mice did not produce toxicities.

Keywords


Ervatamia coronaria; Toxicity; Biochemical parameters; Renal parameters

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