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Identification of flavonoids in the methanolic and aqueous leaf extracts of Schrebera swietenioides Linn.

Anuradha Devi V., Veera Kishore I., Ragha Latha R., Kokkanti Mallikarjuna

Abstract


Plant secondary metabolites provide a scope of developing drugs basing on their specific biological activities. Hence phytochemical and pharmacological screening of medicinal plants has been extensively carried out. In the present paper, flavonoids were isolated from methanolic and aqueous extracts of Schrebera swietenioides which is widel used in the treatment of leprosy, diabetes, and liver problems. Chromatographic methods like TLC and HPLC were used for the separation and identification of flavonoids present in methanolic and aqueous leaf extract was studied. The chromatographic methods available for the separation of flavonoids in TLC and HPLC were adopted for the study. Three compounds were identified in TLC study in methanolic and aqueous leaf extracts. In HPLC analysis, peaks corresponding to flavonoids were obtained and were identified by comparing with literature and confirm that methanolic extract contains Rutin, Quercetin and Myricetin where as in aqueous extract Rutin and Quercetin were observed. The isolated compounds were found to be having potent anti diabetic activity. This proves that the anti-diabetic activity of S. swietenioides was due to the presence of these flavonoid bio-active compounds.

Keywords


Schrebera swietenioides, Flavonoids, The anti-diabetic activity, TLC, HPLC

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References


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DOI: https://doi.org/10.21746/aps.2018.7.4.6

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